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  1. Dokkyo Journal of Medical Sciences
  2. 33(2) 2006

The Effects of Olprinone Hydrochloride on Hemodynamics : Status in Patients with Moderate and Severe Preoperative Cardiac Function Under Cardiac Surgery

https://dmu.repo.nii.ac.jp/records/439
https://dmu.repo.nii.ac.jp/records/439
219da472-0060-459b-9209-d6be98e988aa
名前 / ファイル ライセンス アクション
KJ00004701719.pdf KJ00004701719.pdf (557.7 kB)
Item type [ELS]学術雑誌論文 / Journal Article(1)
公開日 2017-05-24
タイトル
タイトル The Effects of Olprinone Hydrochloride on Hemodynamics : Status in Patients with Moderate and Severe Preoperative Cardiac Function Under Cardiac Surgery
言語 en
言語
言語 eng
キーワード
言語 en
主題 olprinone hydrochloride
キーワード
言語 en
主題 coronary artery bypass grafting
キーワード
言語 en
主題 cardiac function
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
雑誌書誌ID
収録物識別子 AA00629581
論文名よみ
タイトル The Effects of Olprinone Hydrochloride on Hemodynamics : Status in Patients with Moderate and Severe Preoperative Cardiac Function Under Cardiac Surgery
著者 Arai, Takero

× Arai, Takero

en Arai, Takero

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Okuda, Yasuhisa

× Okuda, Yasuhisa

en Okuda, Yasuhisa

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著者所属(英)
en
Department of Anesthesiology, Dokkyo Medical University, Koshigaya Hospital
著者所属(英)
en
Department of Anesthesiology, Dokkyo Medical University, Koshigaya Hospital
記事種別(日)
内容記述タイプ Other
内容記述 原著
記事種別(英)
内容記述タイプ Other
内容記述 Original
抄録(英)
内容記述タイプ Other
内容記述 We compared the effects of olprinone hydrochloride in 22 patients undergoing coronary artery bypass grafting, to compare effectiveness and the relationship to hemodynamics. Patients were divided into 2 groups : Group M, with moderate preoperative cardiac function (Left ventricular ejection fraction 45% and cardiac index >2.5;n=10) ; and Group S, with severe (Left ventricular ejection fraction <__-45% and cardiac index <__-2.5;n=12) preoperative cardiac function. At time of weaning from cardiopulmonary bypass, both groups were administered 15μg/kg olprinone hydrochloride as a bolus, then 0.1μg/kg/min olprinone hydrochloride was infused continuously. In both groups, olprinone significantly increased cardiac index and stroke volume index. Rate of increase in cardiac index and stroke volume index after administration of olprinone was higher for Group S than that of Group M for an extended period of time. Ratio of increase in heart rate was significantly lower for Group S than that of M group. Thus, olprinone hydrochloride can effectively improve hemodynamics after emergence from cardiac bypass in cardiac surgical patients with severe preoperative cardiac function.
書誌情報 Dokkyo journal of medical sciences

巻 33, 号 2, p. 117-123, 発行日 2006-07-25
ISSN
収録物識別子タイプ ISSN
収録物識別子 03855023
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