| Item type |
学術雑誌論文 / Journal Article(1) |
| タイトル |
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|
タイトル |
Endothelial Regeneration in Repair from Vascular Injury and Stem Cell Biology |
| 言語 |
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|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
atherosclerosis |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
endothelial regeneration |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
angiogenesis |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
adipose-derived regenerative cells |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
multi-lineage differentiating stress enduring cell |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Inoue, Teruo
Simon, Daniel I
Murohara, Toyoaki
Dezawa, Mari
Inoue, Ken-ichi
Sakuma, Masashi
Toyoda, Shigeru
|
| 著者所属 |
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|
値 |
Center for Advanced Medical Science Research, Dokkyo Medical University;Department of Cardiovascular Medicine, Dokkyo Medical University School of Medicine |
| 著者所属 |
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|
値 |
UH Cleveland Medical Center, Case Western Reserve University |
| 著者所属 |
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|
値 |
Department of Cardiology, Nagoya University Graduate School of Medicine |
| 著者所属 |
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|
値 |
Department of Stem Cell Biology and Histology, Tohoku University Graduate School of Medicine |
| 著者所属 |
|
|
値 |
Center for Advanced Medical Science Research, Dokkyo Medical University |
| 著者所属 |
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|
値 |
Department of Cardiovascular Medicine, Dokkyo Medical University School of Medicine |
| 著者所属 |
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|
値 |
Department of Cardiovascular Medicine, Dokkyo Medical University School of Medicine |
| 書誌情報 |
Dokkyo Medical Journal
巻 1,
号 1,
p. 4-13,
発行日 2022-03
|
| 抄録 |
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|
内容記述タイプ |
Abstract |
|
内容記述 |
In the process of repair from tissue injury,‘regeneration’naturally occurs in-vivo. Also in the vessels, mechanical stress induces injury, but then the injured sites are repaired by tissue regeneration. Our research has long focused on stem cell biology in vascular injury and repair. In the process of repair from vascular injury, bone marrow-derived stem cells including endothelial progenitor cells (EPCs) are recruited, and the EPCs differentiate into endothelial cells, leading to endothelial regeneration. On the other hand, also in the cardiovascular scene, regenerative medicine has been clinically applied as vascular and myocardial regeneration. We have been promoting vascular regeneration therapy (angiogenesis therapy) for critical limb ischemia, using adipose-derived regenerative (stem) cells (ADRCs). Now, we are planning a new project for research and clinical application of regenerative medicine, using the multi-lineage differentiating stress enduring (Muse) cell as a novel cell source. |
| 記事種別 |
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|
値 |
Review Article |
| 出版者 |
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|
出版者 |
Dokkyo Medical Society |
| ISSN |
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|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
2436-5211 |
| DOI |
|
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|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.51040/dkmj.1.1_4 |
DKMJ-1-1-Inoue-Fulltext (1.2 MB)
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