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Evaluations of Left Anterior Descendant Coronary Artery Stenosis by Transthoracic Doppler Echocardiography as Compared with Physiological Parameters Measured by Pressure Wire
https://dmu.repo.nii.ac.jp/records/5116
https://dmu.repo.nii.ac.jp/records/51165a3a8aba-eb1d-4abf-83d9-fa8c87ce8db9
| 名前 / ファイル | ライセンス | アクション |
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DKMJ-1-1-Ito-Fulltext (839.4 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||||||
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| タイトル | ||||||||||||||
| タイトル | Evaluations of Left Anterior Descendant Coronary Artery Stenosis by Transthoracic Doppler Echocardiography as Compared with Physiological Parameters Measured by Pressure Wire | |||||||||||||
| 言語 | ||||||||||||||
| 言語 | eng | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | Doppler echocardiography | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | coronary artery disease | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | coronary blood flow | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | coronary stenosis | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | coronary intervention | |||||||||||||
| 資源タイプ | ||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||
| 資源タイプ | journal article | |||||||||||||
| 著者 |
Ito, Nobuhiko
× Ito, Nobuhiko
× Harada, Osamu
× Horinaka, Shigeo
× Ishimitsu, Toshihiko
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| 著者所属 | ||||||||||||||
| Department of Cardiology, Kanto Central Hospital | ||||||||||||||
| 著者所属 | ||||||||||||||
| Department of Laboratory, Kanto Central Hospital | ||||||||||||||
| 著者所属 | ||||||||||||||
| Department of Nephrology and Hypertension, Dokkyo Medical University | ||||||||||||||
| 著者所属 | ||||||||||||||
| Department of Nephrology and Hypertension, Dokkyo Medical University | ||||||||||||||
| 書誌情報 |
Dokkyo Medical Journal 巻 1, 号 1, p. 22-29, 発行日 2022-03 |
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| 抄録 | ||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||
| 内容記述 | Background: In coronary angiography (CAG), fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) are widely measured for evaluating physiological ischemia and indication for percutaneous coronary intervention (PCI). On the other hand, the progress of ultrasonic devices and techniques have enabled the evaluation of coronary blood flow by non-invasive transthoracic echocardiography. Although, its application is limited to left anterior descending coronary artery (LAD). Objective: To investigate the correlation between the evaluation of physiological ischemia by catheterization and the evaluation of flow velocities by transthoracic echocardiography. Methods: In patients who underwent CAG for diagnosing angina, physiological evaluation of coronary blood flow was performed using pressure wire in LAD lesions. Transthoracic coronary echocardiography was also performed to evaluate the coronary blood flow velocity in the same lesions. Results: The peak diastolic flow velocity of the stenotic portion (V-stn) and the ratio of peak diastolic flow velocities of the stenotic and the reference portions (V-stn/V-ref) showed higher correlation efficient (r) values with FFR (r=0.561, p<0.001 and r=0.612, p<0.001, respectively) than with % diameter stenosis by quantitative CAG (r=0.481, p<0.001). On the other hand, iFR was also correlated with V-stn (r=0.411, p<0.001) but the correlation with V-stn/V-ref was not significant. According to the Receiver operating characteristic curve analysis, the V-stn and the V-stn/V-ref values corresponding to FFR=0.80 were 0.56 m/s (sensitivity 0.90, specificity 0.69) and 2.05 (sensitivity 0.85, specificity 0.69), respectively. Especially, almost all the patients with V-stn>1m/s or V-stn/V-ref >3 had FFR<0.80 and were sent for revascularization therapy. Conclusion: In LAD region of coronary artery, transthoracic coronary echocardiography is considered to be a practically useful method for evaluating physiological ischemia and indication for PCI. |
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| 記事種別 | ||||||||||||||
| Original | ||||||||||||||
| 出版者 | ||||||||||||||
| 出版者 | Dokkyo Medical Society | |||||||||||||
| ISSN | ||||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||||
| 収録物識別子 | 2436-5211 | |||||||||||||
| DOI | ||||||||||||||
| 識別子タイプ | DOI | |||||||||||||
| 関連識別子 | 10.51040/dkmj.1.1_22 | |||||||||||||
