| Item type |
学術雑誌論文 / Journal Article(1) |
| タイトル |
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タイトル |
Serum Heat-shock Protein 70 Level for Predicting Postoperative Morbidity in Patients with Esophageal Cancer |
| 言語 |
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言語 |
eng |
| キーワード |
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主題Scheme |
Other |
|
主題 |
Esophageal cancer |
| キーワード |
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主題Scheme |
Other |
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主題 |
esophagectomy |
| キーワード |
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主題Scheme |
Other |
|
主題 |
morbidity, HSP70 |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 著者 |
Nakajima, Masanobu
Muroi, Hiroto
Kikuchi, Maiko
Maeda, Yasunori
Ueta, Yu
Wakayama, Shigeyoshi
Takise, Shuhei
Takayanagi, Masashi
Fujita, Junki
Kubo, Tsukasa
Ihara, Keisuke
Nakagawa, Masatoshi
Matsudera, Shotaro
Watanabe, Shun
Yamaguchi, Takeshi
Suzuki, Kan
Morita, Shinji
Nakamura, Takatoshi
Kojima, Kazuyuki
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| 著者所属 |
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Department of Upper Gastrointestinal Surgery, Dokkyo Medical University, Tochigi, Japan |
| 著者所属 |
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Department of Upper Gastrointestinal Surgery, Dokkyo Medical University, Tochigi, Japan |
| 著者所属 |
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Department of Upper Gastrointestinal Surgery, Dokkyo Medical University, Tochigi, Japan |
| 著者所属 |
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Department of Upper Gastrointestinal Surgery, Dokkyo Medical University, Tochigi, Japan |
| 著者所属 |
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Department of Upper Gastrointestinal Surgery, Dokkyo Medical University, Tochigi, Japan |
| 著者所属 |
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Department of Upper Gastrointestinal Surgery, Dokkyo Medical University, Tochigi, Japan |
| 著者所属 |
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Department of Upper Gastrointestinal Surgery, Dokkyo Medical University, Tochigi, Japan |
| 著者所属 |
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Department of Upper Gastrointestinal Surgery, Dokkyo Medical University, Tochigi, Japan |
| 著者所属 |
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Department of Surgical Oncology, Dokkyo Medical University Graduate School of Medicine, Tochigi, Japan |
| 著者所属 |
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Department of Upper Gastrointestinal Surgery, Dokkyo Medical University, Tochigi, Japan |
| 著者所属 |
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Department of Surgical Oncology, Dokkyo Medical University Graduate School of Medicine, Tochigi, Japan |
| 著者所属 |
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Department of Upper Gastrointestinal Surgery, Dokkyo Medical University, Tochigi, Japan |
| 著者所属 |
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Department of Surgical Oncology, Dokkyo Medical University Graduate School of Medicine, Tochigi, Japan |
| 著者所属 |
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Department of Surgical Oncology, Dokkyo Medical University Graduate School of Medicine, Tochigi, Japan |
| 著者所属 |
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Department of Surgical Oncology, Dokkyo Medical University Graduate School of Medicine, Tochigi, Japan |
| 著者所属 |
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Department of Surgical Oncology, Dokkyo Medical University Graduate School of Medicine, Tochigi, Japan |
| 著者所属 |
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Department of Upper Gastrointestinal Surgery, Dokkyo Medical University, Tochigi, Japan |
| 著者所属 |
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Department of Surgical Oncology, Dokkyo Medical University Graduate School of Medicine, Tochigi, Japan |
| 著者所属 |
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Department of Upper Gastrointestinal Surgery, Dokkyo Medical University, Tochigi, Japan |
| 書誌情報 |
Dokkyo Medical Journal
巻 1,
号 2,
p. 92-98,
発行日 2022-06
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| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
Background: Heat-shock protein 70 (HSP70) is important in host responses to various stresses. This study analyzed the correlation between preoperative serum concentrations of HPS70 and postoperative morbidity in patients with esophageal cancer.
Materials and Methods: Serum samples were obtained preoperatively from 31 patients with esophageal squamous cell carcinoma. Serum HSP70 concentrations were measured by enzyme-linked immunosorbent assay and the relationships between serum HSP70 level and postoperative morbidities were analyzed.
Results: The mean concentration of serum HSP70 was 9.71 ng/ml. When patients were dichotomized relative to this cutoff, no significant relationships between perioperative inflammatory markers and serum HSP70 level were observed. The incidence of postoperative complications was significantly lower in patients with HSP70 ≥9.71 ng/ml (p=0.0281).
Conclusion: Preoperative serum level of HSP70 was significantly correlated with postoperative morbidities in patients with esophageal cancer. Therefore, enhancing the HSP70 level prior to invasive surgery could be a feasible strategy to prevent morbidity. |
| 記事種別 |
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Original |
| 出版者 |
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出版者 |
Dokkyo Medical Society |
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
2436-5211 |
| DOI |
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識別子タイプ |
DOI |
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関連識別子 |
10.51040/dkmj.1.2_92 |
DKMS-1-2-Nakajima-Fulltext (146.1 kB)
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