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  1. Dokkyo Medical Journal
  2. 1(4) 2022

Substantia Nigra Hyperechogenicity in Parkinson's Disease and Related Disorders: A Follow-up Study

https://dmu.repo.nii.ac.jp/records/5368
https://dmu.repo.nii.ac.jp/records/5368
9dcf0560-b912-49af-95f3-3bf0df6ef159
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DKMJ-1-4-14.pdf DKMJ-1-4-Fujita-Fulltext (126.7 kB)
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Item type 学術雑誌論文 / Journal Article(1)
タイトル
タイトル Substantia Nigra Hyperechogenicity in Parkinson's Disease and Related Disorders: A Follow-up Study
言語
言語 eng
キーワード
主題Scheme Other
主題 Parkinson's disease
キーワード
主題Scheme Other
主題 atypical parkinsonian syndrome
キーワード
主題Scheme Other
主題 substantia nigra hyperechogenicity
キーワード
主題Scheme Other
主題 transcranial sonography
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 Fujita, Hideaki

× Fujita, Hideaki

en Fujita, Hideaki

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Horie, Junichi

× Horie, Junichi

en Horie, Junichi

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Watanabe, Yuji

× Watanabe, Yuji

en Watanabe, Yuji

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Sakuramoto, Hirotaka

× Sakuramoto, Hirotaka

en Sakuramoto, Hirotaka

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Numao, Ayaka

× Numao, Ayaka

en Numao, Ayaka

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Takekawa, Hidehiro

× Takekawa, Hidehiro

en Takekawa, Hidehiro

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Ogaki, Keitaro

× Ogaki, Keitaro

en Ogaki, Keitaro

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Hirata, Koichi

× Hirata, Koichi

en Hirata, Koichi

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Suzuki, Keisuke

× Suzuki, Keisuke

en Suzuki, Keisuke

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著者所属
値 Department of Neurology, Dokkyo Medical University, Tochigi, Japan
著者所属
値 Department of Neurology, Dokkyo Medical University, Tochigi, Japan
著者所属
値 Department of Neurology, Dokkyo Medical University, Tochigi, Japan
著者所属
値 Department of Neurology, Dokkyo Medical University, Tochigi, Japan
著者所属
値 Department of Neurology, Dokkyo Medical University, Tochigi, Japan
著者所属
値 Department of Neurology, Dokkyo Medical University, Tochigi, Japan Center of Medical Ultrasonics, Dokkyo Medical University Hospital, Tochigi, Japan Stroke Center, Dokkyo Medical University Hospital, Tochigi, Japan
著者所属
値 Department of Neurology, Dokkyo Medical University, Tochigi, Japan
著者所属
値 Department of Neurology, Dokkyo Medical University, Tochigi, Japan
著者所属
値 Department of Neurology, Dokkyo Medical University, Tochigi, Japan
書誌情報 Dokkyo Medical Journal

巻 1, 号 4, p. 367-372, 発行日 2022-12
抄録
内容記述タイプ Abstract
内容記述 Background: Previous studies have shown that the hyperechogenic area of the substantia nigra (SN) does not change over the disease course in patients with Parkinson's disease (PD). However, longitudinal changes in SN echogenicity in patients with atypical parkinsonian syndrome (APS) remain unclear. We evaluated the change in SN hyperechogenic area over time in patients with PD and those with APS, including multiple system atrophy (MSA) and progressive supranuclear palsy (PSP).

Methods: A total of 22 patients with parkinsonism (14 PD, aged 71.0 ± 8.3 years; 8 APS (6 PSP and 2 MSA), aged 69.9 ± 9.6 years) who underwent transcranial sonography twice (≥6 months apart) were included in this study. Patients with insufficient temporal bone windows were excluded.

Results: The mean interval between examinations was 24.7 ± 15.3 months. No differences were detected in the hyperechogenic SN area between the first and second examinations (all patients, 0.17 ± 0.09 cm2 vs. 0.17 ± 0.08 cm2, p = 0.67; PD, 0.20 ± 0.08 cm2 vs. 0.20 ± 0.08 cm2, p = 0.45; APS, 0.11 ± 0.06 cm2 vs. 0.12 ± 0.06 cm2, p = 0.37, respectively). In both groups, there were no correlations between the hyperechogenic SN area and disease duration or severity.

Conclusion: The hyperechogenic SN area did not change over the disease course in PD or APS patients.
記事種別
値 Short Communication
出版者
出版者 Dokkyo Medical Society
ISSN
収録物識別子タイプ ISSN
収録物識別子 2436-522X
DOI
識別子タイプ DOI
関連識別子 10.51040/dkmj.2022-019
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