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Clinical Relevance of the Standardized Uptake Value (Suv) in Staging Breast Cancer with FDG-PET/CT
https://dmu.repo.nii.ac.jp/records/611
https://dmu.repo.nii.ac.jp/records/6110b873040-b276-473b-bbe5-33c5c840d685
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
KJ00005058715.pdf (1.2 MB)
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| Item type | [ELS]学術雑誌論文 / Journal Article(1) | |||||||
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| 公開日 | 2017-05-24 | |||||||
| タイトル | ||||||||
| タイトル | Clinical Relevance of the Standardized Uptake Value (Suv) in Staging Breast Cancer with FDG-PET/CT | |||||||
| 言語 | en | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題 | FDG-PET/CT-SUVmax-Breast cancer-Lymph node spread-Metastasis | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | journal article | |||||||
| 雑誌書誌ID | ||||||||
| 収録物識別子 | AA00629581 | |||||||
| 論文名よみ | ||||||||
| タイトル | Clinical Relevance of the Standardized Uptake Value (Suv) in Staging Breast Cancer with FDG-PET/CT | |||||||
| 著者 |
Zytoon, Ashraf Anas
× Zytoon, Ashraf Anas
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| 著者所属(英) | ||||||||
| en | ||||||||
| PET Center, Dokkyo Medical University | ||||||||
| 記事種別(日) | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | 原著 | |||||||
| 記事種別(英) | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | Original | |||||||
| 抄録(英) | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | Purpose : FDG-PET/CT with standardized uptake value (SUV) estimation was applied to breast cancer patients for the purpose of preoperative evaluation of the extent of the disease. Methods : FDG-PET/CT was performed preoperatively in 71 patients with breast cancer, and the maximum standardized uptake value (SUVmax) of tumors, as well as combination of SUVmax and tumor marker CA 15-3 were investigated for a significant association with lymph node spread and distant metastasis. Results : Tumor SUVmax high (>3.1) was found to have a reliable predictive value for lymph node spread (sensitivity 82.9%, specificity 75%, P<0.0001), while SUVmax-High (>3.8)/CA 15-3-Elevated was found to be superior for the prediction of metastasis (sensitivity ; 75%, specificity ; 92.7%, P=0.0001). Moreover, linear regression analysis identified the best correlation was between SUVmax-High (>3.1) with lymph node spread {correlation coefficient (r^2)=0.580, P=0.0001}, and SUVmax-High (>3.8)/CA 15-3-Elevated with distant metastasis {correlation coefficient (r^2)=0.677, P<0.0001}. Conclusions : SUVmax is a reliable predictor of lymph node spread, and if combined with tumor marker assay (CA 15-3) labeled SUVmax-High/CA 15-3-Elevated is sufficient for the early detection of breast cancer metastasis. This outcome suggests that the FDG-PET/CT findings with SUV calculation could have a strong positive impact on breast cancer patients. | |||||||
| 書誌情報 |
Dokkyo journal of medical sciences 巻 34, 号 3, p. 193-204, 発行日 2007-10-01 |
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| ISSN | ||||||||
| 収録物識別子タイプ | ISSN | |||||||
| 収録物識別子 | 03855023 | |||||||
