Item type |
[ELS]学術雑誌論文 / Journal Article(1) |
公開日 |
2017-05-24 |
タイトル |
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タイトル |
Influence of Obstructive Sleep Apnea on Diastolic Heart Failure |
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言語 |
en |
言語 |
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言語 |
eng |
キーワード |
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言語 |
en |
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主題 |
diastolic heart failure |
キーワード |
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言語 |
en |
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主題 |
obstructive sleep apnea |
キーワード |
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言語 |
en |
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主題 |
brain natriuretic peptide |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
雑誌書誌ID |
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収録物識別子 |
AA00629581 |
論文名よみ |
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タイトル |
Influence of Obstructive Sleep Apnea on Diastolic Heart Failure |
著者 |
Arikawa, Takuo
Matsuda, Ryuko
Araki, Hidehiko
Toyoda, Shigetu
Kikuchi, Akiko
Tokura, Michiaki
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著者所属(英) |
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en |
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Department of Cardiology and Pneumology Dokkyo Medical University School of Medicine |
著者所属(英) |
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en |
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Department of Cardiology and Pneumology Dokkyo Medical University School of Medicine |
著者所属(英) |
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en |
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Department of Cardiology and Pneumology Dokkyo Medical University School of Medicine |
著者所属(英) |
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en |
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Department of Cardiology and Pneumology Dokkyo Medical University School of Medicine |
著者所属(英) |
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en |
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Department of Cardiology and Pneumology Dokkyo Medical University School of Medicine |
著者所属(英) |
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en |
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Department of Cardiology and Pneumology Dokkyo Medical University School of Medicine |
記事種別(日) |
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内容記述タイプ |
Other |
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内容記述 |
原著 |
記事種別(英) |
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内容記述タイプ |
Other |
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内容記述 |
Original |
抄録(英) |
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内容記述タイプ |
Other |
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内容記述 |
Heart failure is frequently complicated by obstructive sleep apnea, which raises blood pressure and arrhythmiaand worsens prognosis. However, the incidence and influence of obstructive sleep apnea in patientswith diastolic heart failure is unknown. We hypothesized that patients with diastolic heart failurecomplicated by obstructive sleep apnea may have a worse outcome compared to those without obstructivesleep apnea. The study included 49 patients with an ejection fraction ≥ 50 %, of whom 34 had diastolic heartfailure and 15 did not have diastolic heart failure. The patients were examined in a sleep study and byechocardiography. Brain natriuretic peptide (BNP) levels were determined at admission and 1, 6 and 12months thereafter. The prevalence of obstructive sleep apnea in patients with diastolic heart failure( 18/34,53 %) was significantly higher than that in those without diastolic heart failure (3/15, 20 %)(p=0.032).BNP levels were high at admission in patients with diastolic heart failure, but then decreased gradually inthose without obstructive sleep apnea. However, BNP in patients with diastolic heart failure and obstructivesleep apnea remained high and was significantly elevated compared to the level in patients without obstructivesleep apnea at 6 and 12 months after admission. Patients with diastolic heart failure and obstructivesleep apnea showed prolongation of elevated BNP, indicating that complication of diastolic heart failure byobstructive sleep apnea may aggravate cardiac function. |
書誌情報 |
Dokkyo journal of medical sciences
巻 36,
号 1,
p. 1-8,
発行日 2009-03-25
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ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
03855023 |