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  1. Dokkyo Journal of Medical Sciences
  2. 36(1) 2009

Influence of Obstructive Sleep Apnea on Diastolic Heart Failure

https://dmu.repo.nii.ac.jp/records/748
https://dmu.repo.nii.ac.jp/records/748
a55a435a-8e45-432d-8d9d-0dae023bfc77
名前 / ファイル ライセンス アクション
KJ00006349559.pdf KJ00006349559.pdf (92.4 kB)
Item type [ELS]学術雑誌論文 / Journal Article(1)
公開日 2017-05-24
タイトル
タイトル Influence of Obstructive Sleep Apnea on Diastolic Heart Failure
言語 en
言語
言語 eng
キーワード
言語 en
主題 diastolic heart failure
キーワード
言語 en
主題 obstructive sleep apnea
キーワード
言語 en
主題 brain natriuretic peptide
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
雑誌書誌ID
収録物識別子 AA00629581
論文名よみ
タイトル Influence of Obstructive Sleep Apnea on Diastolic Heart Failure
著者 Arikawa, Takuo

× Arikawa, Takuo

en Arikawa, Takuo

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Matsuda, Ryuko

× Matsuda, Ryuko

en Matsuda, Ryuko

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Araki, Hidehiko

× Araki, Hidehiko

en Araki, Hidehiko

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Toyoda, Shigetu

× Toyoda, Shigetu

en Toyoda, Shigetu

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Kikuchi, Akiko

× Kikuchi, Akiko

en Kikuchi, Akiko

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Tokura, Michiaki

× Tokura, Michiaki

en Tokura, Michiaki

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著者所属(英)
en
Department of Cardiology and Pneumology Dokkyo Medical University School of Medicine
著者所属(英)
en
Department of Cardiology and Pneumology Dokkyo Medical University School of Medicine
著者所属(英)
en
Department of Cardiology and Pneumology Dokkyo Medical University School of Medicine
著者所属(英)
en
Department of Cardiology and Pneumology Dokkyo Medical University School of Medicine
著者所属(英)
en
Department of Cardiology and Pneumology Dokkyo Medical University School of Medicine
著者所属(英)
en
Department of Cardiology and Pneumology Dokkyo Medical University School of Medicine
記事種別(日)
内容記述タイプ Other
内容記述 原著
記事種別(英)
内容記述タイプ Other
内容記述 Original
抄録(英)
内容記述タイプ Other
内容記述 Heart failure is frequently complicated by obstructive sleep apnea, which raises blood pressure and arrhythmiaand worsens prognosis. However, the incidence and influence of obstructive sleep apnea in patientswith diastolic heart failure is unknown. We hypothesized that patients with diastolic heart failurecomplicated by obstructive sleep apnea may have a worse outcome compared to those without obstructivesleep apnea. The study included 49 patients with an ejection fraction ≥ 50 %, of whom 34 had diastolic heartfailure and 15 did not have diastolic heart failure. The patients were examined in a sleep study and byechocardiography. Brain natriuretic peptide (BNP) levels were determined at admission and 1, 6 and 12months thereafter. The prevalence of obstructive sleep apnea in patients with diastolic heart failure( 18/34,53 %) was significantly higher than that in those without diastolic heart failure (3/15, 20 %)(p=0.032).BNP levels were high at admission in patients with diastolic heart failure, but then decreased gradually inthose without obstructive sleep apnea. However, BNP in patients with diastolic heart failure and obstructivesleep apnea remained high and was significantly elevated compared to the level in patients without obstructivesleep apnea at 6 and 12 months after admission. Patients with diastolic heart failure and obstructivesleep apnea showed prolongation of elevated BNP, indicating that complication of diastolic heart failure byobstructive sleep apnea may aggravate cardiac function.
書誌情報 Dokkyo journal of medical sciences

巻 36, 号 1, p. 1-8, 発行日 2009-03-25
ISSN
収録物識別子タイプ ISSN
収録物識別子 03855023
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