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  1. Dokkyo Journal of Medical Sciences
  2. 45(1) 2018

Results of Hepatitis B Vaccination 3 Years After a Primary Vaccine Series in Medical Students

https://dmu.repo.nii.ac.jp/records/1500
https://dmu.repo.nii.ac.jp/records/1500
3a7c215e-0dc2-4f4c-b2ae-94223b258fcd
名前 / ファイル ライセンス アクション
DJMS-45-1-2.pdf DJMS-45-1-Ohyatsu-本文 (214.3 kB)
Item type 学術雑誌論文 / Journal Article(1)
タイトル
タイトル Results of Hepatitis B Vaccination 3 Years After a Primary Vaccine Series in Medical Students
言語
言語 eng
キーワード
主題Scheme Other
主題 hepatitis B virus
キーワード
主題Scheme Other
主題 HBV
キーワード
主題Scheme Other
主題 hepatitis B(HB)vaccine
キーワード
主題Scheme Other
主題 anti-HBs
キーワード
主題Scheme Other
主題 additional vaccination
キーワード
主題Scheme Other
主題 medical students
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 Ohyatsu, Mariko

× Ohyatsu, Mariko

en Ohyatsu, Mariko

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Ishikawa, Yayoi

× Ishikawa, Yayoi

en Ishikawa, Yayoi

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Chibana, Yoko

× Chibana, Yoko

en Chibana, Yoko

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Watanabe, Naomi

× Watanabe, Naomi

en Watanabe, Naomi

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Ohrui, Masami

× Ohrui, Masami

en Ohrui, Masami

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Tsuchida, Kohei

× Tsuchida, Kohei

en Tsuchida, Kohei

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Tominaga, Keiichi

× Tominaga, Keiichi

en Tominaga, Keiichi

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Murohisa, Toshimitsu

× Murohisa, Toshimitsu

en Murohisa, Toshimitsu

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Iijima, Makoto

× Iijima, Makoto

en Iijima, Makoto

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Hiraishi, Hideyuki

× Hiraishi, Hideyuki

en Hiraishi, Hideyuki

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著者所属
Department of Health Care, Dokkyo Medical University Hospital, Tochigi, Japan
著者所属
Department of Health Care, Dokkyo Medical University Hospital, Tochigi, Japan
著者所属
Department of Health Care, Dokkyo Medical University Hospital, Tochigi, Japan
著者所属
Department of Health Care, Dokkyo Medical University Hospital, Tochigi, Japan
著者所属
Department of Health Care, Dokkyo Medical University Hospital, Tochigi, Japan:Health Service Center, Dokkyo Medical University, Tochigi, Japan
著者所属
Department of Gastroenterology, Dokkyo Medical University, Tochigi, Japan
著者所属
Department of Gastroenterology, Dokkyo Medical University, Tochigi, Japan
著者所属
Department of Gastroenterology, Dokkyo Medical University, Tochigi, Japan
著者所属
Department of Gastroenterology, Dokkyo Medical University, Tochigi, Japan
著者所属
Department of Gastroenterology, Dokkyo Medical University, Tochigi, Japan
書誌情報 Dokkyo Journal of Medical Sciences

巻 45, 号 1, p. 1-8, 発行日 2018-03-25
要旨
内容記述タイプ Other
内容記述 Objective:To investigate the significance of additional hepatitis B (HB) vaccination in medical students who were unresponsive to a primary vaccine series or those who had lost antibody to hepatitis B surface antigen (anti-HBs).

Methods:Subjects were followed up for 3 years after completion of a primary HB vaccine series. One additional dose was given to those who lost the anti-HBs within 3 years after the initial series, while 3 doses were given to those who had not responded to the initial vaccination. Subjects:100 medical students (59 men and 41 women;mean age on admission to university, 19.4±1.6 years) enrolled at the School of Medicine, Dokkyo Medical University in April 2012.

Results:The rate of positivity for anti-HBs was 98% soon after completion of the primary HB vaccine series and decreased without the need for additional vaccination to 79%, 61%, and 55% at 1, 2, and 3 years after the primary series, respectively. Eighteen vaccinated subjects (18%) lost the anti-HBs 2 years after the primary series, and all of them responded to 1 additional dose. Another 18 successfully vaccinated subjects (18%) were anti-HBs negative both 1 and 2 years after the primary series;17 of them responded to 1 additional dose. As for 2 subjects (2%) who were unresponsive to the primary series, 1 became anti-HBs-positive for the first time after 3 additional doses given 2 years after the primary series.

Conclusion:A number of students became or remained anti-HBs negative after the primary HB vaccination, indicating that its timing and dose of additional vaccination need to be studied further to evaluate its utility.
記事種別
Original
出版者
出版者 獨協医学会
ISSN
収録物識別子タイプ ISSN
収録物識別子 03855023
書誌レコードID
収録物識別子タイプ NCID
収録物識別子 AA00629581
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