| Item type |
学術雑誌論文 / Journal Article(1) |
| タイトル |
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タイトル |
Results of Hepatitis B Vaccination 3 Years After a Primary Vaccine Series in Medical Students |
| 言語 |
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言語 |
eng |
| キーワード |
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主題Scheme |
Other |
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主題 |
hepatitis B virus |
| キーワード |
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主題Scheme |
Other |
|
主題 |
HBV |
| キーワード |
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主題Scheme |
Other |
|
主題 |
hepatitis B(HB)vaccine |
| キーワード |
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主題Scheme |
Other |
|
主題 |
anti-HBs |
| キーワード |
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主題Scheme |
Other |
|
主題 |
additional vaccination |
| キーワード |
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主題Scheme |
Other |
|
主題 |
medical students |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 著者 |
Ohyatsu, Mariko
Ishikawa, Yayoi
Chibana, Yoko
Watanabe, Naomi
Ohrui, Masami
Tsuchida, Kohei
Tominaga, Keiichi
Murohisa, Toshimitsu
Iijima, Makoto
Hiraishi, Hideyuki
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| 著者所属 |
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Department of Health Care, Dokkyo Medical University Hospital, Tochigi, Japan |
| 著者所属 |
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Department of Health Care, Dokkyo Medical University Hospital, Tochigi, Japan |
| 著者所属 |
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Department of Health Care, Dokkyo Medical University Hospital, Tochigi, Japan |
| 著者所属 |
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Department of Health Care, Dokkyo Medical University Hospital, Tochigi, Japan |
| 著者所属 |
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Department of Health Care, Dokkyo Medical University Hospital, Tochigi, Japan:Health Service Center, Dokkyo Medical University, Tochigi, Japan |
| 著者所属 |
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Department of Gastroenterology, Dokkyo Medical University, Tochigi, Japan |
| 著者所属 |
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Department of Gastroenterology, Dokkyo Medical University, Tochigi, Japan |
| 著者所属 |
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Department of Gastroenterology, Dokkyo Medical University, Tochigi, Japan |
| 著者所属 |
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Department of Gastroenterology, Dokkyo Medical University, Tochigi, Japan |
| 著者所属 |
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Department of Gastroenterology, Dokkyo Medical University, Tochigi, Japan |
| 書誌情報 |
Dokkyo Journal of Medical Sciences
巻 45,
号 1,
p. 1-8,
発行日 2018-03-25
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| 要旨 |
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内容記述タイプ |
Other |
|
内容記述 |
Objective：To investigate the significance of additional hepatitis B （HB） vaccination in medical students who were unresponsive to a primary vaccine series or those who had lost antibody to hepatitis B surface antigen （anti-HBs）.
Methods：Subjects were followed up for 3 years after completion of a primary HB vaccine series. One additional dose was given to those who lost the anti-HBs within 3 years after the initial series, while 3 doses were given to those who had not responded to the initial vaccination. Subjects：100 medical students （59 men and 41 women；mean age on admission to university, 19.4±1.6 years） enrolled at the School of Medicine, Dokkyo Medical University in April 2012.
Results：The rate of positivity for anti-HBs was 98％ soon after completion of the primary HB vaccine series and decreased without the need for additional vaccination to 79％, 61％, and 55％ at 1, 2, and 3 years after the primary series, respectively. Eighteen vaccinated subjects （18％） lost the anti-HBs 2 years after the primary series, and all of them responded to 1 additional dose. Another 18 successfully vaccinated subjects （18％） were anti-HBs negative both 1 and 2 years after the primary series；17 of them responded to 1 additional dose. As for 2 subjects （2％） who were unresponsive to the primary series, 1 became anti-HBs-positive for the first time after 3 additional doses given 2 years after the primary series.
Conclusion：A number of students became or remained anti-HBs negative after the primary HB vaccination, indicating that its timing and dose of additional vaccination need to be studied further to evaluate its utility. |
| 記事種別 |
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Original |
| 出版者 |
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出版者 |
獨協医学会 |
| ISSN |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
03855023 |
| 書誌レコードID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA00629581 |
| 表示順 |
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2 |
DJMS-45-1-Ohyatsu-本文 (214.3 kB)
