| Item type |
学術雑誌論文 / Journal Article(1) |
| タイトル |
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|
タイトル |
Effectiveness of Anti-PD-1 Antibody Monotherapy for the Primary Malignant Melanoma of the Esophagus： A Case Report |
| 言語 |
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|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
malignant melanoma |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
esophagus |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
nivolumab |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Muroi, Hiroto
Nakajima, Masanobu
Kikuchi, Maiko
Takahashi, Masakazu
Shida, Yosuke
Ihara, Keisuke
Ito, Jun
Yamaguchi, Satoru
Sasaki, Kinro
Kato, Hiroyuki
|
| 著者所属 |
|
|
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First Department of Surgery, Dokkyo Medical University |
| 著者所属 |
|
|
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First Department of Surgery, Dokkyo Medical University |
| 著者所属 |
|
|
|
First Department of Surgery, Dokkyo Medical University |
| 著者所属 |
|
|
|
First Department of Surgery, Dokkyo Medical University |
| 著者所属 |
|
|
|
First Department of Surgery, Dokkyo Medical University |
| 著者所属 |
|
|
|
First Department of Surgery, Dokkyo Medical University |
| 著者所属 |
|
|
|
First Department of Surgery, Dokkyo Medical University |
| 著者所属 |
|
|
|
First Department of Surgery, Dokkyo Medical University |
| 著者所属 |
|
|
|
First Department of Surgery, Dokkyo Medical University |
| 著者所属 |
|
|
|
First Department of Surgery, Dokkyo Medical University |
| 書誌情報 |
Dokkyo Journal Of Medical Sciences
巻 45,
号 2,
p. 73-79,
発行日 2018-07-25
|
| 要旨 |
|
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内容記述タイプ |
Other |
|
内容記述 |
Primary malignant melanoma of the esophagus（PMME）is extraordinarily rare with a high degree of malignancy and poor prognosis, and a standard therapy remains to be established. The anti-PD-1 antibody nivolumab is a promising agent for various cancers. To our knowledge, this is the first case report of PMME where a complete response was achieved using nivolumab. We report an 80-year-old woman who was diagnosed with PMME with bone metastasis and lymph node metastases. Although dacarbazine combined chemotherapy was performed and continued for six cycles, the primary tumor progressed and liver metastases appeared. The patient then received nivolumab monotherapy. After three cycles, nivolumab monotherapy for PMME resulted in a complete response as shown by positron emission tomography, computed tomography, and esophagogastroduodenoscopy. In our case, nivolumab exerted a curative effect on PMME, thus suggesting that nivolumab can be effective in the treatment of this rare disease. |
| 記事種別 |
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Case Report |
| 出版者 |
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出版者 |
獨協医学会 |
| ISSN |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
03855023 |
| 書誌レコードID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AA00629581 |
DJMS-45-2-Muroi-本文 (369.3 kB)
