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  1. Dokkyo Journal of Medical Sciences
  2. 32(1) 2005

Immunohistochemical Study of Cytokeratin Related Protein Expression in Patients with Trichilemmal Tumors and Squamous Cell Carcinoma of the Skin

https://dmu.repo.nii.ac.jp/records/318
https://dmu.repo.nii.ac.jp/records/318
9b59f0a7-fba2-45f6-8a1a-5095edc76750
名前 / ファイル ライセンス アクション
KJ00004161884.pdf KJ00004161884.pdf (1.2 MB)
Item type [ELS]学術雑誌論文 / Journal Article(1)
公開日 2017-05-24
タイトル
タイトル Immunohistochemical Study of Cytokeratin Related Protein Expression in Patients with Trichilemmal Tumors and Squamous Cell Carcinoma of the Skin
言語 en
言語
言語 eng
キーワード
言語 en
主題 trichilemmal carcinoma
キーワード
言語 en
主題 squamous cell carcinoma
キーワード
言語 en
主題 cytokeratin
キーワード
言語 en
主題 involucrin
キーワード
言語 en
主題 immunohistochemistry
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
雑誌書誌ID
収録物識別子 AA00629581
論文名よみ
タイトル Immunohistochemical Study of Cytokeratin Related Protein Expression in Patients with Trichilemmal Tumors and Squamous Cell Carcinoma of the Skin
著者 Hama, Naoto

× Hama, Naoto

en Hama, Naoto

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著者所属(英)
en
Department of Dermatology, Dokkyo University School of Medicine
記事種別(日)
内容記述タイプ Other
内容記述 原著
記事種別(英)
内容記述タイプ Other
内容記述 Original
抄録(英)
内容記述タイプ Other
内容記述 Trichilemmal tumors can be either benign and malignant skin tumors arising from the outer root sheath of the hair follicle. It remains unknown whether malignant trichilemmal tumors can be differentiated from squamous cell carcinoma (SCC). In order to differentiate malignant trichilemmal tumors from SCC, we studied cytokeratin-related protein and involucrin expression immunohistochemically. Twenty-three trichilemmal carcinomas (TLC), 4 malignant proliferating tricholemmal tumors (MPTT) and 25 SCCs were studied. All the skin biopsy specimens were subjected to staining with anti-cytokeratin and anti-involucrin antibodies immunohistochemically, and the expression of cytokeratins and involucrin were investigated. The occurrence rate of cytoketatin 1 positive staining in TLC was significantly less than that in SCC (P<0.05), while that of cytokeratin 19 positivity in SCC was significantly less than that in TLC (P<0.01). These results demonstrate that immunohistochemical staining with anti-cytokeratin 1 and anti-cytokeratin 19 antibodies is useful for the differential diagnosis of TLC and SCC.
書誌情報 Dokkyo journal of medical sciences

巻 32, 号 1, p. 7-12, 発行日 2005-03-25
ISSN
収録物識別子タイプ ISSN
収録物識別子 03855023
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