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Immunohistochemical Study of Cytokeratin Related Protein Expression in Patients with Trichilemmal Tumors and Squamous Cell Carcinoma of the Skin
https://dmu.repo.nii.ac.jp/records/318
https://dmu.repo.nii.ac.jp/records/3189b59f0a7-fba2-45f6-8a1a-5095edc76750
名前 / ファイル | ライセンス | アクション |
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Item type | [ELS]学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-05-24 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Immunohistochemical Study of Cytokeratin Related Protein Expression in Patients with Trichilemmal Tumors and Squamous Cell Carcinoma of the Skin | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題 | trichilemmal carcinoma | |||||
キーワード | ||||||
言語 | en | |||||
主題 | squamous cell carcinoma | |||||
キーワード | ||||||
言語 | en | |||||
主題 | cytokeratin | |||||
キーワード | ||||||
言語 | en | |||||
主題 | involucrin | |||||
キーワード | ||||||
言語 | en | |||||
主題 | immunohistochemistry | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
雑誌書誌ID | ||||||
収録物識別子 | AA00629581 | |||||
論文名よみ | ||||||
タイトル | Immunohistochemical Study of Cytokeratin Related Protein Expression in Patients with Trichilemmal Tumors and Squamous Cell Carcinoma of the Skin | |||||
著者 |
Hama, Naoto
× Hama, Naoto |
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著者所属(英) | ||||||
en | ||||||
Department of Dermatology, Dokkyo University School of Medicine | ||||||
記事種別(日) | ||||||
内容記述タイプ | Other | |||||
内容記述 | 原著 | |||||
記事種別(英) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Original | |||||
抄録(英) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Trichilemmal tumors can be either benign and malignant skin tumors arising from the outer root sheath of the hair follicle. It remains unknown whether malignant trichilemmal tumors can be differentiated from squamous cell carcinoma (SCC). In order to differentiate malignant trichilemmal tumors from SCC, we studied cytokeratin-related protein and involucrin expression immunohistochemically. Twenty-three trichilemmal carcinomas (TLC), 4 malignant proliferating tricholemmal tumors (MPTT) and 25 SCCs were studied. All the skin biopsy specimens were subjected to staining with anti-cytokeratin and anti-involucrin antibodies immunohistochemically, and the expression of cytokeratins and involucrin were investigated. The occurrence rate of cytoketatin 1 positive staining in TLC was significantly less than that in SCC (P<0.05), while that of cytokeratin 19 positivity in SCC was significantly less than that in TLC (P<0.01). These results demonstrate that immunohistochemical staining with anti-cytokeratin 1 and anti-cytokeratin 19 antibodies is useful for the differential diagnosis of TLC and SCC. | |||||
書誌情報 |
Dokkyo journal of medical sciences 巻 32, 号 1, p. 7-12, 発行日 2005-03-25 |
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ISSN | ||||||
収録物識別子 | 03855023 |