| Item type |
学術雑誌論文 / Journal Article(1) |
| タイトル |
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|
タイトル |
Relationship between Fluorine-18 Fluorodeoxyglucose PET/CT Uptake and the Plasma Cell Infiltration Rate in the Bone Marrow of Multiple Myeloma Patients |
| 言語 |
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|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
FDG uptake |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Multiple Myeloma |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
PET/CT |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Plasma Cell |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Ganbold, Tsengel
Nakagami, Yoshihiro
Imamura, Kensuke
Misu, Yosuke
Kumazawa, Mariko
Arakawa, Hiroaki
Ichikawa, Motoshi
Mitani, Kinuko
Ishida, Kazuyuki
Kano, Daisuke
Hosokawa, Shota
Kaji, Yasushi
|
| 著者所属 |
|
|
値 |
Department of Radiology, School of Medicine, Dokkyo Medical University |
| 著者所属 |
|
|
値 |
Department of Radiology, School of Medicine, Dokkyo Medical University;PET Center, Dokkyo Medical University Hospital |
| 著者所属 |
|
|
値 |
Department of Radiology, School of Medicine, Dokkyo Medical University |
| 著者所属 |
|
|
値 |
Department of Radiology, School of Medicine, Dokkyo Medical University |
| 著者所属 |
|
|
値 |
Department of Radiology, School of Medicine, Dokkyo Medical University |
| 著者所属 |
|
|
値 |
Department of Radiology, School of Medicine, Dokkyo Medical University |
| 著者所属 |
|
|
値 |
Department of Hematology and Oncology, School of Medicine, Dokkyo Medical University |
| 著者所属 |
|
|
値 |
Department of Hematology and Oncology, School of Medicine, Dokkyo Medical University |
| 著者所属 |
|
|
値 |
Department of Diagnostic Pathology, School of Medicine, Dokkyo Medical University |
| 著者所属 |
|
|
値 |
Department of Pharmacy, National Cancer Center Hospital East |
| 著者所属 |
|
|
値 |
Department of Radiation Science, Graduate School of Health Sciences, Hirosaki University |
| 著者所属 |
|
|
値 |
Department of Radiology, School of Medicine, Dokkyo Medical University |
| 書誌情報 |
Dokkyo Medical Journal
巻 1,
号 1,
p. 63-71,
発行日 2022-03
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Background: The current study investigated the relationship between maximum standardized uptake values (SUVmax) on Fluorine-18 Fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) and the plasma cell proliferation percentage in the bone marrow as well as hematological and biochemical test results of patients with multiple myeloma (MM). Moreover, we identified if differences exist in parameters across different types of paraproteins and stages.
Material and methods: Patients clinically and pathologically diagnosed with MM between 2012 and 2019 were selected from the database of the Dokkyo Medical University Hospital, Japan. Unsuitable patients were excluded from the current study to avoid false uptake. We examined 60 patients and hematological and biochemical tests were recorded and evaluated. The percentage of plasma cells in bone marrow aspiration samples was calculated. In PET/CT images, the SUVmax of the region of interest of the right posterior ilium (aspiration area) was measured. Relationships were examined using Spearman’s correlation coefficient, and differences were identified using the Kruskal-Wallis test with SPSS.
Results: A positive correlation was observed between FDG uptake and the percentage of plasma cells (r = 0.672, P < 0.0001).
Conclusion: Increased FDG uptake by bone marrow correlated with the percentage of plasma cells. Some
biochemical and hematological parameters were statistically different according to the stage and types of
paraproteins. PET/CT is suitable for evaluating the condition of a patient and the activity of the MM lesion. |
| 記事種別 |
|
|
値 |
Original |
| 出版者 |
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|
出版者 |
Dokkyo Medical Society |
| ISSN |
|
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
2436-5211 |
| DOI |
|
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|
識別子タイプ |
DOI |
|
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関連識別子 |
10.51040/dkmj.1.1_63 |
DKMS-1-1-Ganbold-Fulltext (495.7 kB)
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