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  1. Dokkyo Medical Journal
  2. 1(2) 2022

Association Analysis between Cyanotic Congenital Heart Disease and Nephropathy in Children

https://dmu.repo.nii.ac.jp/records/5238
https://dmu.repo.nii.ac.jp/records/5238
88fdb005-d370-42cb-99a2-7a655549e619
名前 / ファイル ライセンス アクション
DKMJ-1-2-1.pdf DKMJ-1-2-Talolena-Fulltext (150.0 kB)
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Item type 学術雑誌論文 / Journal Article(1)
タイトル
タイトル Association Analysis between Cyanotic Congenital Heart Disease and Nephropathy in Children
言語
言語 eng
キーワード
主題Scheme Other
主題 congenital heart disease
キーワード
主題Scheme Other
主題 cyanotic congenital heart disease
キーワード
主題Scheme Other
主題 hematuria
キーワード
主題Scheme Other
主題 nephropathy
キーワード
主題Scheme Other
主題 proteinuria
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ journal article
著者 Talolena, Helen W.M

× Talolena, Helen W.M

en Talolena, Helen W.M

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Rahman, Mahrus A.

× Rahman, Mahrus A.

en Rahman, Mahrus A.

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Soemyarso, Ninik Asmaningsih

× Soemyarso, Ninik Asmaningsih

en Soemyarso, Ninik Asmaningsih

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著者所属
値 Department of Pediatrics, Faculty of Medicine Universitas Airlangga 60132, Surabaya, East Java, Indonesia, Dr. Soetomo General Academic Hospital, 60286, Surabaya, East Java, Indonesia
著者所属
値 Department of Pediatrics, Faculty of Medicine Universitas Airlangga 60132, Surabaya, East Java, Indonesia, Dr. Soetomo General Academic Hospital, 60286, Surabaya, East Java, Indonesia
著者所属
値 Department of Pediatrics, Faculty of Medicine Universitas Airlangga 60132, Surabaya, East Java, Indonesia, Dr. Soetomo General Academic Hospital, 60286, Surabaya, East Java, Indonesia
書誌情報 Dokkyo Medical Journal

巻 1, 号 2, p. 85-91, 発行日 2022-06
抄録
内容記述タイプ Abstract
内容記述 Cyanotic congenital heart disease (CCHD) causes chronic hypoxia in several organs, especially kidneys. The association between CCHD and nephropathy has been known although the mechanism is not yet completely understood. This study was aimed to investigate the association between CCHD and the incidence of nephropathy in children.
 This case-control study was conducted at the Pediatric Outpatient Installation of the Integrated Heart Service Center (IHSC) and Children’s Inpatient Room, Dr. Soetomo General Hospital Surabaya from January to May 2021. The inclusion criteria included children with CCHD and normal children aged 1-18 years who visited IHSC and Pediatric Clinic. Informed consent was signed by the parents. Demographic data, proteinuria, and hematuria were analyzed to find the association with the incidence of CCHD in children.
 Eighty-five participants participated in the study, of which seven were excluded, leaving 78 eligible participants. Forty-four CCHD patients and 34 control patients had a difference in oxygen saturation (67.70 ± 11.21 to 94.94 ± 0.98%). Sixty-four percent of the participants were diagnosed with tetralogy of Fallot (TOF), while 29.5% were diagnosed with double outlet right ventricle (DORV). There was a significant association between CCHD with proteinuria and hematuria (p = 0.001, r = 0.481; p = 0.001, r = 0.375). Significant associations was also found in proteinuria and hematuria with CCHD with a diagnosis of DORV and TOF (p = 0.014, p = 0.002).
 As a conclusion, a significant association was found between CCHD with the incidence of proteinuria and hematuria. Nephropathy screening is needed in patients suffering from CCHD to detect renal damage.
記事種別
値 Original
出版者
出版者 Dokkyo Medical Society
ISSN
収録物識別子タイプ ISSN
収録物識別子 2436-5211
DOI
識別子タイプ DOI
関連識別子 10.51040/dkmj.1.2_85
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