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Relation of Adiposity Rebound age to Serum Small Dense Low-density Lipoprotein in Young Childhood
https://dmu.repo.nii.ac.jp/records/641
https://dmu.repo.nii.ac.jp/records/641c5ea5925-ad8c-4eca-9dcb-cd6ac7ffce92
| 名前 / ファイル | ライセンス | アクション |
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KJ00005058745.pdf (588.0 kB)
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| Item type | [ELS]学術雑誌論文 / Journal Article(1) | |||||||
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| 公開日 | 2017-05-24 | |||||||
| タイトル | ||||||||
| タイトル | Relation of Adiposity Rebound age to Serum Small Dense Low-density Lipoprotein in Young Childhood | |||||||
| 言語 | en | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題 | body-mass index | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題 | adiposity rebound | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題 | obesity | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題 | small dense LDL | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題 | metabolic syndrome | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題 | insulin resistance | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | journal article | |||||||
| 雑誌書誌ID | ||||||||
| 収録物識別子 | AA00629581 | |||||||
| 論文名よみ | ||||||||
| タイトル | Relation of Adiposity Rebound age to Serum Small Dense Low-density Lipoprotein in Young Childhood | |||||||
| 著者 |
Yamazaki, Yuzuru
× Yamazaki, Yuzuru
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| 著者所属(英) | ||||||||
| en | ||||||||
| Department of Pediatrics, Dokkyo Medical University | ||||||||
| 記事種別(日) | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | 原著 | |||||||
| 記事種別(英) | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | Original | |||||||
| 抄録(英) | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | The number of patients with childhood obesity is increasing worldwide. The age of adiposity rebound (AR), the age when body mass starts to rise after transient decrease after birth, is thought to have a predictive value of obesity in adulthood. In order to elucidate whether the early gain of weight is related to the future occurrence of metabolic syndrome, the author examined the relationship between the time of AR and the prevalence of children having atherogenic small dense LDL (SDLDL) in serum at 12 years of age in Fujioka town in Japan. A total of 215 children (114 boys and 101 girls) who were born between 1995 and 1996 have been enrolled in this study as a prospective cohort. Annual measurements of body-mass index (BMI) from 4 months to 12 years were carried out. We defined the age of AR as the age when the lowest BMI occurred during this period. At 12 years of age, serum concentrations of lipids including of SDLDL and lipoproteins were measured. As results children who exhibited an earlier AR had the higher BMI value at 12 years of age (p<0.01) in both sexes. The prevalence of SDLDL decreased progressively from 15.0% in children in whom AR occurred before the age of 4 years to 0% in those in whom AR occurred after 6 years. Furthermore, the earlier AR was associated with elevated triglyceride (p<0.05) and apolipoprotein B (p<0.01) levels and decreased HDL-cholesterol levels (p<0.05). In conclusion the present longitudinal population-based study indicates that children who exhibit AR at a younger age seem to be predisposed towards the future development of metabolic syndrome. Thus, it is possible to identify high-risk children with metabolic syndrome prospectively by measuring early adiposity rebound. | |||||||
| 書誌情報 |
Dokkyo journal of medical sciences 巻 35, 号 1, p. 7-12, 発行日 2008-03-01 |
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| ISSN | ||||||||
| 収録物識別子タイプ | ISSN | |||||||
| 収録物識別子 | 03855023 | |||||||
