{"_buckets": {"deposit": "2498656f-3de7-4597-9571-f10bf2c05bdc"}, "_deposit": {"created_by": 3, "id": "807", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "807"}, "status": "published"}, "_oai": {"id": "oai:dmu.repo.nii.ac.jp:00000807", "sets": ["51"]}, "author_link": ["7021", "7022", "3418", "7020", "7024", "4720", "7023"], "item_2_biblio_info_12": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2009-10-25", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "3", "bibliographicPageEnd": "134", "bibliographicPageStart": "131", "bibliographicVolumeNumber": "36", "bibliographic_titles": [{"bibliographic_title": "Dokkyo journal of medical sciences"}]}]}, "item_2_description_11": {"attribute_name": "抄録(英)", "attribute_value_mlt": [{"subitem_description": "PURPOSE:The aim of this study was to investigate changes in spleen size, the level of chromogranin Aas a tumor marker, and the relationship between these two parameters before and 3 months after selectiveinternal radiation therapy (SIRT) for non-resectable liver metastases from neuroendocrine tumor (NET).Our first serious adverse event with this relatively new treatment is also discussed.METHODS:A retrospective review of a prospective database identified patients with non-resectable livermetastases from NET who underwent SIRT between 2003 and 2007. Patients who underwent CT scansbefore and 3 months after treatment were included. The patients were divided into two groups:those withand without a 20 % or more increase in splenic volume on the CT scans. The percentages of patients showinga tumor marker response in the two groups were then comparedRESULTS:Fourteen patients were included in the present analysis. A tumor marker response was seenin 6 of 7 patients( 85.7%) who showed an increase in splenic volume of\u003e20%, and in 3 of 7 patients( 42.9%) without an increase in splenic volume (p=0.266). There was one death as a result of oesophageal varicealbleeding due to portal hypertension at 9 months after treatment.CONCLUSION:Splenic enlargement after SIRT may be associated with tumor marker response, althoughthis could not be confirmed statistically in this study due to the small number of patients. Long-termsplenomegaly and portal hypertension may be important complications of SIRT. This issue needs to be investigatedfurther using a larger number of patients and longer follow-up.", "subitem_description_type": "Other"}]}, "item_2_description_15": {"attribute_name": "表示順", "attribute_value_mlt": [{"subitem_description": "2", "subitem_description_type": "Other"}]}, "item_2_description_16": {"attribute_name": "アクセション番号", "attribute_value_mlt": [{"subitem_description": "KJ00006364179", "subitem_description_type": "Other"}]}, "item_2_description_9": {"attribute_name": "記事種別(英)", "attribute_value_mlt": [{"subitem_description": "Original", "subitem_description_type": "Other"}]}, "item_2_source_id_1": {"attribute_name": "雑誌書誌ID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00629581", "subitem_source_identifier_type": "NCID"}]}, "item_2_source_id_19": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "03855023", "subitem_source_identifier_type": "ISSN"}]}, "item_2_text_7": {"attribute_name": "著者所属(英)", "attribute_value_mlt": [{"subitem_text_language": "en", "subitem_text_value": "Department of Surgery, St. George Hospital, University of New South Wales, Sydney, Australia"}, {"subitem_text_language": "en", "subitem_text_value": "Department of Surgery, St. George Hospital, University of New South Wales, Sydney, Australia"}, {"subitem_text_language": "en", "subitem_text_value": "Department of Surgery, St. George Hospital, University of New South Wales, Sydney, Australia:Department of Surgery, Teishinkai Hospitals, Ibaraki, Japan"}, {"subitem_text_language": "en", "subitem_text_value": "Department of Surgery, St. George Hospital, University of New South Wales, Sydney, Australia"}, {"subitem_text_language": "en", "subitem_text_value": "Department of Surgery, St. George Hospital, University of New South Wales, Sydney, Australia"}, {"subitem_text_language": "en", "subitem_text_value": "Department of Surgery, St. George Hospital, University of New South Wales, Sydney, Australia"}, {"subitem_text_language": "en", "subitem_text_value": "Department of Surgery, St. George Hospital, University of New South Wales, Sydney, Australia"}]}, "item_2_title_3": {"attribute_name": "論文名よみ", "attribute_value_mlt": [{"subitem_title": "Splenomegaly and Tumor Marker Response Following Selective Internal Radiation Therapy for Non-Resectable Liver Metastases from Neuroendocrine Tumor"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Shehata, Mena", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "3418", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yan, Kenneth", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "7020", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Itoh, Seiji", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "4720", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "King, Julie", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "7021", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Glenn, Derek", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "7022", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Quinn, Richard", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "7023", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Morris, David Lawson", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "7024", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-05-24"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00006364179.pdf", "filesize": [{"value": "64.0 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 64000.0, "url": {"label": "KJ00006364179.pdf", "url": "https://dmu.repo.nii.ac.jp/record/807/files/KJ00006364179.pdf"}, "version_id": "e7673cea-ea76-41dd-961c-08c0ace1b168"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "internal radiation therapy, SIRT, neuroendocrine tumor, liver metastasis, splenomegaly", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Splenomegaly and Tumor Marker Response Following Selective Internal Radiation Therapy for Non-Resectable Liver Metastases from Neuroendocrine Tumor", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Splenomegaly and Tumor Marker Response Following Selective Internal Radiation Therapy for Non-Resectable Liver Metastases from Neuroendocrine Tumor", "subitem_title_language": "en"}]}, "item_type_id": "2", "owner": "3", "path": ["51"], "permalink_uri": "https://dmu.repo.nii.ac.jp/records/807", "pubdate": {"attribute_name": "公開日", "attribute_value": "2017-05-24"}, "publish_date": "2017-05-24", "publish_status": "0", "recid": "807", "relation": {}, "relation_version_is_last": true, "title": ["Splenomegaly and Tumor Marker Response Following Selective Internal Radiation Therapy for Non-Resectable Liver Metastases from Neuroendocrine Tumor"], "weko_shared_id": 3}