WEKO3
アイテム
Studies on Relationship between nbl (S3a) mRNA Levels, Cell Density, and Chemosensitivity in Various Rat and Human Cell Lines
https://dmu.repo.nii.ac.jp/records/213
https://dmu.repo.nii.ac.jp/records/21332cc70ae-b2e6-4fb4-968b-2d3570c5fd25
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
KJ00004091306.pdf (949.8 kB)
|
|
| Item type | [ELS]学術雑誌論文 / Journal Article(1) | |||||||
|---|---|---|---|---|---|---|---|---|
| 公開日 | 2017-05-24 | |||||||
| タイトル | ||||||||
| タイトル | Studies on Relationship between nbl (S3a) mRNA Levels, Cell Density, and Chemosensitivity in Various Rat and Human Cell Lines | |||||||
| 言語 | en | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題 | Cultured cells | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題 | Chemosensitivity | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題 | nbl (S3a) | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題 | Cell density | |||||||
| キーワード | ||||||||
| 言語 | en | |||||||
| 主題 | Alamar Blue | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
| 資源タイプ | journal article | |||||||
| 雑誌書誌ID | ||||||||
| 収録物識別子 | AA00629581 | |||||||
| 論文名よみ | ||||||||
| タイトル | Studies on Relationship between nbl (S3a) mRNA Levels, Cell Density, and Chemosensitivity in Various Rat and Human Cell Lines | |||||||
| 著者 |
Nemoto, Kazuhiro
× Nemoto, Kazuhiro
|
|||||||
| 著者所属(英) | ||||||||
| en | ||||||||
| First Department of Surgery, Dokkyo University School of Medicine | ||||||||
| 記事種別(日) | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | 原著 | |||||||
| 記事種別(英) | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | Original | |||||||
| 抄録(英) | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | Cytocidal effects of anti-cancer drugs such as cisplatin, 5-fluorouracil (5-FU), and actinomycin D on various cell lines were investigated using Alamar Blue. Actinomycin D, cisplatin and 5-FU showed significant cytocidal effects at 1μg/ml, 10μg/ml and 50μg/ml respectively, on cultured cells after 24 h incubation at 37℃. The cytocidal effects increased at a low cell density but reduced at a high cell density in various cell lines. The expression level of one of the ribosomal proteins, nbl (S3a), was measured by northern blot analysis and real time-polymerase chain reaction. The relationship between the nbl mRNA level and drug effects was then investigated for 8 rat and 10 human cell lines. An inverse correlation between chemosensitivity and nbl mRNA level was observed in both rat and human cell lines. | |||||||
| 書誌情報 |
Dokkyo journal of medical sciences 巻 31, 号 1, p. 7-16, 発行日 2004-03-25 |
|||||||
| ISSN | ||||||||
| 収録物識別子タイプ | ISSN | |||||||
| 収録物識別子 | 03855023 | |||||||
