{"_buckets": {"deposit": "8888aad9-779d-4940-b1c3-dac84024c454"}, "_deposit": {"created_by": 3, "id": "213", "owners": [3], "pid": {"revision_id": 0, "type": "depid", "value": "213"}, "status": "published"}, "_oai": {"id": "oai:dmu.repo.nii.ac.jp:00000213", "sets": ["29"]}, "author_link": ["740"], "item_2_biblio_info_12": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2004-03-25", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "1", "bibliographicPageEnd": "16", "bibliographicPageStart": "7", "bibliographicVolumeNumber": "31", "bibliographic_titles": [{"bibliographic_title": "Dokkyo journal of medical sciences"}]}]}, "item_2_description_11": {"attribute_name": "抄録(英)", "attribute_value_mlt": [{"subitem_description": "Cytocidal effects of anti-cancer drugs such as cisplatin, 5-fluorouracil (5-FU), and actinomycin D on various cell lines were investigated using Alamar Blue. Actinomycin D, cisplatin and 5-FU showed significant cytocidal effects at 1μg/ml, 10μg/ml and 50μg/ml respectively, on cultured cells after 24 h incubation at 37℃. The cytocidal effects increased at a low cell density but reduced at a high cell density in various cell lines. The expression level of one of the ribosomal proteins, nbl (S3a), was measured by northern blot analysis and real time-polymerase chain reaction. The relationship between the nbl mRNA level and drug effects was then investigated for 8 rat and 10 human cell lines. An inverse correlation between chemosensitivity and nbl mRNA level was observed in both rat and human cell lines.", "subitem_description_type": "Other"}]}, "item_2_description_15": {"attribute_name": "表示順", "attribute_value_mlt": [{"subitem_description": "4", "subitem_description_type": "Other"}]}, "item_2_description_16": {"attribute_name": "アクセション番号", "attribute_value_mlt": [{"subitem_description": "KJ00004091306", "subitem_description_type": "Other"}]}, "item_2_description_8": {"attribute_name": "記事種別(日)", "attribute_value_mlt": [{"subitem_description": "原著", "subitem_description_type": "Other"}]}, "item_2_description_9": {"attribute_name": "記事種別(英)", "attribute_value_mlt": [{"subitem_description": "Original", "subitem_description_type": "Other"}]}, "item_2_source_id_1": {"attribute_name": "雑誌書誌ID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00629581", "subitem_source_identifier_type": "NCID"}]}, "item_2_source_id_19": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "03855023", "subitem_source_identifier_type": "ISSN"}]}, "item_2_text_7": {"attribute_name": "著者所属(英)", "attribute_value_mlt": [{"subitem_text_language": "en", "subitem_text_value": "First Department of Surgery, Dokkyo University School of Medicine"}]}, "item_2_title_3": {"attribute_name": "論文名よみ", "attribute_value_mlt": [{"subitem_title": "Studies on Relationship between nbl (S3a) mRNA Levels, Cell Density, and Chemosensitivity in Various Rat and Human Cell Lines"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Nemoto, Kazuhiro", "creatorNameLang": "en"}], "nameIdentifiers": [{"nameIdentifier": "740", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2017-05-24"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00004091306.pdf", "filesize": [{"value": "949.8 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 949800.0, "url": {"label": "KJ00004091306.pdf", "url": "https://dmu.repo.nii.ac.jp/record/213/files/KJ00004091306.pdf"}, "version_id": "3d55b1d4-9ed0-453b-be7d-263d2478de94"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Cultured cells", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Chemosensitivity", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "nbl (S3a)", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Cell density", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Alamar Blue", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Studies on Relationship between nbl (S3a) mRNA Levels, Cell Density, and Chemosensitivity in Various Rat and Human Cell Lines", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Studies on Relationship between nbl (S3a) mRNA Levels, Cell Density, and Chemosensitivity in Various Rat and Human Cell Lines", "subitem_title_language": "en"}]}, "item_type_id": "2", "owner": "3", "path": ["29"], "permalink_uri": "https://dmu.repo.nii.ac.jp/records/213", "pubdate": {"attribute_name": "公開日", "attribute_value": "2017-05-24"}, "publish_date": "2017-05-24", "publish_status": "0", "recid": "213", "relation": {}, "relation_version_is_last": true, "title": ["Studies on Relationship between nbl (S3a) mRNA Levels, Cell Density, and Chemosensitivity in Various Rat and Human Cell Lines"], "weko_shared_id": 3}