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Serum MMP-9 in Females Have Higher Correlation with DWI-Positive Findings for Carotid Artery Stenting than in Males
https://dmu.repo.nii.ac.jp/records/5358
https://dmu.repo.nii.ac.jp/records/5358c85d9667-d724-484c-85dd-5946511e1621
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
DKMJ-1-4-Tanaka-Fulltext (135.2 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| タイトル | ||||||
| タイトル | Serum MMP-9 in Females Have Higher Correlation with DWI-Positive Findings for Carotid Artery Stenting than in Males | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | MMP-9 | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | DWI-positive findings | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | female | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | CAS | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Tanaka, Yoshihiro
× Tanaka, Yoshihiro× Takigawa, Tomoji× Synmyo, Kei× Anazawa, Toru× Matsumoto, Yoshiyuki× Fujii, Yoshiko× Kanaya, Takahiro× Nariai, Yasuhiko× Sugiura, Yoshiki× Kawamura, Yosuke× Suzuki, Ryotaro× Takano, Issei× Hyodo, Akio× Nagaishi, Masaya× Suzuki, Kensuke |
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| 著者所属 | ||||||
| 値 | Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center | |||||
| 著者所属 | ||||||
| 値 | Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center | |||||
| 著者所属 | ||||||
| 値 | Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center | |||||
| 著者所属 | ||||||
| 値 | Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center | |||||
| 著者所属 | ||||||
| 値 | Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center | |||||
| 著者所属 | ||||||
| 値 | Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center | |||||
| 著者所属 | ||||||
| 値 | Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center | |||||
| 著者所属 | ||||||
| 値 | Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center | |||||
| 著者所属 | ||||||
| 値 | Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center | |||||
| 著者所属 | ||||||
| 値 | Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center | |||||
| 著者所属 | ||||||
| 値 | Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center | |||||
| 著者所属 | ||||||
| 値 | Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center | |||||
| 著者所属 | ||||||
| 値 | Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center | |||||
| 著者所属 | ||||||
| 値 | Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center | |||||
| 著者所属 | ||||||
| 値 | Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center | |||||
| 書誌情報 |
Dokkyo Medical Journal 巻 1, 号 4, p. 292-298, 発行日 2022-12 |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Introduction: Embolus due to plaque rupture is a risk of cerebral infarction for carotid artery stenting (CAS). Female have been controversial as a risk factor for cardiovascular interventions in recent years. MMP-9 has been previously reported to be associated with acute ischemic stroke and to be a potential marker for arteriosclerosis. Therefore, this paper aimed to investigate the gender difference of embolic complications for CAS using MMP-9. Material and Methods: We analyzed 46 consecutive cases of CAS performed with distal balloon protection, including 34 males and 12 females. Serum levels of matrix metalloproteinase (MMP) -9 were measured before and after CAS. Embolic events were examined in Diffusion Weighted Imaging (DWI) on MRI the next day after CAS. Results: 13 cases (28.3%) had DWI-positive findings after CAS, and these results showed a significant gender difference (female 58.3% vs. male 17.6%, p < 0.05). Pre-CAS MMP-9 was significantly higher in females than in males (661.7 vs. 428.1 ng/ml, p < 0.05). Pre-CAS MMP-9 tended to be higher in DWI-positive cases than DWI-negative cases with no significant difference (676.9 vs. 415.0 ng/ml, p = 0.051). Conclusion: High serum MMP-9 in female have correlation with DWI positive findings after CAS. We suggest that high serum MMP-9 have a risk of cerebral infarction for CAS. Considering the results, CAS should be carefully performed, especially in female. |
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| 記事種別 | ||||||
| 値 | Original | |||||
| 出版者 | ||||||
| 出版者 | Dokkyo Medical Society | |||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 2436-522X | |||||
| DOI | ||||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.51040/dkmj.2022-015 | |||||
