| Item type |
学術雑誌論文 / Journal Article(1) |
| タイトル |
|
|
タイトル |
Serum MMP-9 in Females Have Higher Correlation with DWI-Positive Findings for Carotid Artery Stenting than in Males |
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
MMP-9 |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
DWI-positive findings |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
female |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
CAS |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 著者 |
Tanaka, Yoshihiro
Takigawa, Tomoji
Synmyo, Kei
Anazawa, Toru
Matsumoto, Yoshiyuki
Fujii, Yoshiko
Kanaya, Takahiro
Nariai, Yasuhiko
Sugiura, Yoshiki
Kawamura, Yosuke
Suzuki, Ryotaro
Takano, Issei
Hyodo, Akio
Nagaishi, Masaya
Suzuki, Kensuke
|
| 著者所属 |
|
|
|
Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center |
| 著者所属 |
|
|
|
Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center |
| 著者所属 |
|
|
|
Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center |
| 著者所属 |
|
|
|
Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center |
| 著者所属 |
|
|
|
Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center |
| 著者所属 |
|
|
|
Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center |
| 著者所属 |
|
|
|
Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center |
| 著者所属 |
|
|
|
Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center |
| 著者所属 |
|
|
|
Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center |
| 著者所属 |
|
|
|
Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center |
| 著者所属 |
|
|
|
Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center |
| 著者所属 |
|
|
|
Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center |
| 著者所属 |
|
|
|
Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center |
| 著者所属 |
|
|
|
Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center |
| 著者所属 |
|
|
|
Department of Neurosurgery, Dokkyo Medical University Saitama Medical Center |
| 書誌情報 |
Dokkyo Medical Journal
巻 1,
号 4,
p. 292-298,
発行日 2022-12
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Introduction: Embolus due to plaque rupture is a risk of cerebral infarction for carotid artery stenting (CAS). Female have been controversial as a risk factor for cardiovascular interventions in recent years. MMP-9 has been previously reported to be associated with acute ischemic stroke and to be a potential marker for arteriosclerosis.
Therefore, this paper aimed to investigate the gender difference of embolic complications for CAS using MMP-9.
Material and Methods: We analyzed 46 consecutive cases of CAS performed with distal balloon protection, including 34 males and 12 females. Serum levels of matrix metalloproteinase (MMP) -9 were measured before and after CAS. Embolic events were examined in Diffusion Weighted Imaging (DWI) on MRI the next day after CAS.
Results: 13 cases (28.3%) had DWI-positive findings after CAS, and these results showed a significant gender difference (female 58.3% vs. male 17.6%, p < 0.05). Pre-CAS MMP-9 was significantly higher in females than in males (661.7 vs. 428.1 ng/ml, p < 0.05).
Pre-CAS MMP-9 tended to be higher in DWI-positive cases than DWI-negative cases with no significant difference (676.9 vs. 415.0 ng/ml, p = 0.051).
Conclusion: High serum MMP-9 in female have correlation with DWI positive findings after CAS. We suggest that high serum MMP-9 have a risk of cerebral infarction for CAS. Considering the results, CAS should be carefully performed, especially in female. |
| 記事種別 |
|
|
|
Original |
| 出版者 |
|
|
出版者 |
Dokkyo Medical Society |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
2436-522X |
| DOI |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
10.51040/dkmj.2022-015 |
DKMJ-1-4-Tanaka-Fulltext (135.2 kB)
.png)
